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Jan 10, 2023

What does the body of evidence say on the topic of osteoporosis? Plus: we look at a genuinely breakthrough therapy for metastatic melanoma, and Chris lets you in on a troubling “secret” when it comes to travel health insurance! You will also learn what a “dowager’s hump” is and hear Chris sing, and for that we formally apologize.


Block 1:

(2:01) Osteoporosis: what it is; bone cells and how they are assessed


Block 2:

(9:02) Osteoporosis: bone mineral density, T-score and Z-score; can doctors see signs of osteoporosis in the clinic; causes of osteoporosis; treating it: lifestyle changes, supplements, bisphosphonates, and Prolia; screening guidelines


Block 3:

(32:04) Breakthrough therapy for metastatic melanoma: TILs (vs. ipilimumab)


Block 4:

(47:53) Travel insurance caveat



* Theme music: “Fall of the Ocean Queen“ by Joseph Hackl.

* Assistant researcher: Nicholas Koziris


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1) Estrogen does reduce the risk of hip fracture from osteoporosis:


2) Exercise increases bone mineral density in post-menopausal women: &


3) Calcium and vitamin D supplementation and the risk of fractures:


4) Medications can reduce the risk of osteoporotic fractures:


5) Screening guidelines from the US Preventive Services Task Force:


6) Results from the phase III clinical trial comparing TILs to ipilumumab in advanced melanoma:



It’s Not Twitter, But It’ll Do:


1) Jonathan on the Martial Culture Podcast:


2) Jonathan’s article on the Healy:


3) The Hard Fork Podcast:


4) The CTV Montreal News website:


5) The CBC Player:


6) The CJAD website:


7) Odyssey TV:


8) Chris on the CBC, interviewed about mpox:



Time Machine:


1) Our episode on childbirth:


2) Our interview on conspirituality:



Music Credits:


The following music was used for this media project:

Music: 3am Glowsticks by Tim Kulig

Free download:

License (CC BY 4.0):